Industrial enzymes discovery and development is one of the cornerstones of the rapidly growing bio-based chemical or white biotech economy.

With the increasing scarcity of non-renewable fossil raw material the chemical industry as a whole has been highly proactive in the recent years in working out and setting up sustainable and cost-effective alternatives. The bio-based industry is stemming from these recent efforts. Rather than producing chemicals and biomolecules from fuels and chemical synthesis the bio-based industry is striving to produce enzymes and other compounds (chemical intermediates as well as finished products) from living organisms. These products are incorporated as active ingredients in products such as washing powders, textiles and are extensively used now in the paper production processes. This paradigm change in raw material sourcing has only been made possible through the recent advent of the genomic technologies such as high-throughput sequencing and functional annotation of living organisms such as bacteria, fungus and yeasts. These organisms are now more and more widely used as “production facilities”.

Furthermore the extremophiles microorganisms (e.g. organisms living at the poles, in hot water sources or in deep sea water) are a very promising source of new functional products such as enzymes active under very stringent conditions (e.g. high or low temperatures and pH).

Progenus proposes:

  • Expertise in the discovery of new functional bio-based finished products and intermediates through its NGS sequencing and functional automatic genome annotation expertise.
  • Bioinformatics services to identify and introduce specific amino-acids sequence mutations to accommodate industrial enzymes to extreme production process conditions (very high or low T° and / or pH).