Assembly

Sequence assembly consists of aligning and merging fragments of a much longer DNA sequence in order to reconstruct the original sequence. This is the typical next steps after high throughput sequencing. This is needed as DNA sequencing technology cannot read whole genomes in one go, but rather reads small pieces of between 20 and 1000 bases, depending on the technology used.

Progenus is able to assemble genomes of viruses, bacteria and small eukaryotes such as fungi and algae.

The technology used by Progenus to assemble the reads depends on the sequencing technology used. Typically one can quote MIRA, Velvet, WGS and CLC Genomic Workbench as the most widely used programs.

Additional information